Arrhythmias & electrophysiologyDiagnostic or prognostic study
New Criteria to Demonstrate Entrainment and Macro–Re-Entry in Atrial Tachycardias
- diagnostic study testing 2 novel conduction time-based criteria
Authors' conclusion
Conduction time analysis provides a robust and accurate approach for confirming entrainment and macro-re-entry in AT, improving diagnostic precision compared with existing criteria.
Study context
- Population
- Individuals with macro-re-entrant atrial tachycardia, focal atrial tachycardia (real/simulated), and sinus rhythm (technical controls) undergoing overdrive atrial pacingindividuals studied, pacing maneuvers in 104 met inclusion criteria for the primary analysis
- Participants
- 117 individuals
- Comparison
- macro-re-entrant atrial tachycardia (AT) vs focal AT vs sinus rhythm
Performance
As reported in the abstract
Criterion 1: maximal conduction time differences
- Greater in macro-re-entrant AT than in focal AT or controls
- P < 0.001
- Cutoff of 60 milliseconds: sensitivity for detecting macro-re-entry
- 95%
- Cutoff of 60 milliseconds: specificity for detecting macro-re-entry
- 100%
Further findings
Criterion 2: maximal conduction time differences
- Criterion 2: maximal conduction time differences — Greater in macro-re-entrant AT than in focal AT or sinus rhythm controls
- P < 0.001
- Criterion 2: maximal conduction time differences — Cutoff of 63 milliseconds: sensitivity
- 96%
- Criterion 2: maximal conduction time differences — Cutoff of 63 milliseconds: specificity
- 100%
Original publication
New Criteria to Demonstrate Entrainment and Macro–Re-Entry in Atrial Tachycardias. JACC Clin Electrophysiol. Published 10 April 2026. doi:10.1016/j.jacep.2026.02.024
Summarised from the published abstract; every number is checked against it