Arrhythmias & electrophysiology
New technique to achieve total mitral isthmus block: Targeting masked epicardial conductions
Authors' conclusion
After MI block, an additional pacing maneuver from the LLR up to the roof unmasked EC in 32% of patients. Targeting these conductions achieved total MI block in 94% of patients.
Study context
- Population
- Patients ablated for persistent AF with successful pulmonary vein isolation, roof line block and mitral isthmus block
- Participants
- 50 patients
- Outcome
- Prevalence of masked epicardial conduction after mitral isthmus block, and feasibility of targeting it by radiofrequency ablation
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Masked epicardial conduction unmasked by pacing from the left lateral ridge up to the roof
16 of 50 patients
32%
Success of additional ablation to isolate epicardial conduction
81.3%
13/16
Overall total isthmus block
47/50 patients
94%
Observational data: associations, not effects.
Safety
- No complications reported
Original publication
New technique to achieve total mitral isthmus block: Targeting masked epicardial conductions. Heart Rhythm. Published 27 November 2025. doi:10. 1016/ j. hrthm. 2025. 11. 045
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