Cardio-oncology & other

Non-COVID-19 cardiovascular pathology from return-to-play screening in college athletes after COVID-19

HeartPublished Prospective cohort study

Authors' conclusion

Major non-COVID-19 cardiovascular pathology was identified in 1/500 college athletes undergoing return-to-play screening. In athletes without ECG abnormalities, TTE's added value was limited to pathological aortic root dilatation in 1/1000 athletes and minor abnormalities warranting surveillance in 1/160 athletes. Two-thirds of findings were incidental or of uncertain significance.

Study context

Population
College athletes with ECG and TTE after SARS-CoV-2 infection undergoing return-to-play screening, no pre-existing conditions (September 2020–June 2021)
Participants
2,900 athletes
Outcome
Incidental non-COVID-19 CV pathology (major, minor, incidental or uncertain significance)
Methodological detailsmulticentre, nationwide, observational, 45 institutions
  • Multicentre
  • Nationwide
  • Observational
  • 45 institutions

Main finding

As reported in the abstract

Non-COVID-19 CV pathology on ECG and TTE
Major conditions overall
6 (0.2%)
ECG abnormalities
35 (1.2%)
ECG abnormal: TTE abnormalities indicating cardiomyopathy (hypertrophic-1, dilated-1)
2 (5.7%)
ECG abnormal, normal TTE: AF
1
Normal ECG
2865 (98.8%)
Normal ECG: TTE abnormalities
54 (1.9%)
Normal ECG: aortic root dilatation ≥40 mm
3 (5.6%)
Normal ECG: minor abnormalities
15 (27.8%)
Normal ECG: incidental findings
25 (46.3%)
Normal ECG: findings of uncertain significance
11 (20.4%)

Observational data: associations, not effects.

Original publication

Non-COVID-19 cardiovascular pathology from return-to-play screening in college athletes after COVID-19. Heart. Published 17 July 2023. doi:10.1136/heartjnl-2023-322645

Summarised from the published abstract; every number is checked against it

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