Arrhythmias & electrophysiologyCohort study
Non-invasive assessment of left atrial activation using lead V8 during Bachmann bundle pacing
- prospective enrolment of consecutive patients
- prospectively enrolled
Authors' conclusion
NDAT-P-V8 closely reflects the invasively determined timing of the posterolateral LA activation and provides a simple non-invasive marker to assess the effect of BBP on LA activation. Lead V8 may therefore help to assess and optimize atrial activation with BBP.
Study context
- Population
- Patients undergoing an electrophysiology study and ablation (Cohort 1) or bachmann bundle pacing (BBP) lead implantation (Cohort 2)Cohort 1 50 · Cohort 2 50
- Participants
- 50 vs 50
- Exposure
- NDAT-P-V8 against invasively determined coronary sinus (CS) activation timing at the posterolateral LA (Cohort 1); NDAT-P-V8 and iso-V8 to assess the effect of BBP on LA activation (Cohort 2)
- Cohort 1n = 50
- Cohort 2n = 50
Main finding
As reported in the abstract
Correlation of NDAT-P-V8 with latest CS activation (Cohort 1)
r
0.94
P
P < 0.001
Observational data: associations, not effects.
Further findings
Intra-procedural assessment of LA activation with lead V8 (Cohort 2)
- lead V8 facilitated intra-procedural assessment of LA activation
IAB corrected (Cohort 2)
- IAB corrected
- 20/23 (87%)
NDAT-P-V8 (Cohort 2)
- from
- 120 ± 25 ms
- to
- 82 ± 17 ms
- P
- P < 0.001
iso-V8 (Cohort 2)
- from
- 51 ± 22 ms
- to
- 18 ± 17 ms
- P
- P < 0.001
Original publication
Non-invasive assessment of left atrial activation using lead V8 during Bachmann bundle pacing. Europace. Published 25 September 2026. doi:10.1093/europace/euag276
Summarised from the published abstract; every number is checked against it