Heart failure & cardiomyopathiesDiagnostic or prognostic study
Non-invasive estimation of right atrial pressure using magnetic resonance imaging: a development and validation study
- development and validation study
- independent held-out test-set cohort stratified by right atrial pressure (RAP) category
Authors' conclusion
An MRI model incorporating abdominal venous and hepatic tissue biomarkers provides a clinically useful, well-calibrated approach for estimating invasive RAP.
Study context
- Population
- Adults who underwent clinically indicated magnetic resonance imaging (MRI) and right heart catheterization within 48 h between 2016 and 2025development 125 · held-out test-set cohort 56
- Participants
- 181 adults
- Comparison
- MRI-based model for predicting invasive RAP
- developmentn = 125
- held-out test-set cohortn = 56
Further findings
Model performance, development cohort
- adjusted R2
- 0.698
- residual standard deviation
- 2.58 mmHg
- remained consistent across three internal validation approaches
Held-out test-set validation
- R2
- 0.621
- root-mean-square error
- 2.78 mmHg
- mean absolute error
- 2.07 mmHg
- concordance coefficient
- 0.777
Calibration in the testing set
- intercept
- + 0.18
- slope
- 0.92
- integrated calibration index
- 0.65 mmHg
Discrimination for elevated RAP
- area under the curve (>5 mmHg)
- 0.749
- area under the curve (>10 mmHg)
- 0.949
- area under the curve (>15 mmHg)
- 0.965
Original publication
Non-invasive estimation of right atrial pressure using magnetic resonance imaging: a development and validation study. Eur Heart J Cardiovasc Imaging. Published 30 August 2026. doi:10.1093/ehjci/jeag205
Summarised from the published abstract; every number is checked against it