Coronary disease & ACSMeta-analysis
Non-occupational physical activity and all-cause mortality in patients with coronary heart disease: a dose–response meta-analysis
- Systematic review and dose-response meta-analysis of prospective cohort studies
- two-stage random-effects
- restricted cubic splines
Authors' conclusion
Higher non-occupational PA was associated with lower all-cause mortality in CHD, particularly at low-to-moderate levels.
Study context
- Population
- Patients with coronary heart disease (CHD)
- Participants
- 176,862 patients · 17 studies
- Comparison
- Non-occupational physical activity (PA) dose vs 0 mMET-h/week
- Outcome
- All-cause mortality (dose-response curve over 0-40 mMET-h/week)
Pooled result
As reported in the abstract
All-cause mortality
Each group vs 0 mMET-h/weekRelative risk (95% CI)
8.75 mMET-h/week38% lower
0.62(0.54–0.73)
17.5 mMET-h/week39% lower
0.61(0.47–0.79)
30 mMET-h/weekimprecise; only 8 of 17 studies had data to this knot
0.92(0.51–1.67)
- Non-linear inverse association
- P for non-linearity <0.001
Original publication
Non-occupational physical activity and all-cause mortality in patients with coronary heart disease: a dose–response meta-analysis. Eur J Prev Cardiol. Published 30 September 2026. doi:10.1093/eurjpc/zwag510
Summarised from the published abstract; every number is checked against it