Arrhythmias & electrophysiologyResearch article
Novel Approach to Lead Extraction, Utilizing Vibration Energy
- first-in-human study
- 3 phases: bench experiments, animal studies, first-in-human study
- consecutive patients
Authors' conclusion
This novel vibration-based extraction technique exhibited excellent safety and efficiency profiles in preclinical and initial human study, potentially offering a simple, rapid, and safe alternative to conventional extraction methods.
Study context
- Population
- Patients requiring lead extraction; animals with varying lead implant durationsconsecutive patients requiring a total of 18 lead extractions · animal studies 13 · first-in-human study 10
- Participants
- 10 patients
- Outcome
- Complete procedural success and absence of major complications
- Follow-up
- during the procedure and at 1-month follow-up
Main finding
As reported in the abstract
Complete extraction achieved in all 10 cases (18 leads [12 pacing, 4 implantable cardiac-defibrillator, and 2 coronary sinus])
10
Secondary outcomes
Bench experiments
- Established optimal vibration parameters for lead extraction
Animal studies
- Animals with long-term implants (up to 5 years), all leads successfully extracted without significant tissue damage
- 9
- Leads (pacing and implantable cardiac-defibrillator)
- 6 pacing and 3 implantable cardiac-defibrillator
- Confirmed safety of high-frequency vibration application to an implanted pacing lead
Lead dwell time and vibration time (human study)
- Mean dwell time
- 48.6 ± 21.74 months (21-78 months)
- Mean lead vibration time
- 40 seconds (6-176 seconds)
Original publication
Novel Approach to Lead Extraction, Utilizing Vibration Energy. JACC Clin Electrophysiol. Published 8 April 2026. doi:10.1016/j.jacep.2026.02.039
Summarised from the published abstract; every number is checked against it