Arrhythmias & electrophysiologyMechanistic study
Novel systematic processing of cardiac magnetic resonance imaging identifies target regions associated with infarct-related ventricular tachycardia
- Translational study
- experimental pig model
- multicentre clinical validation
Authors' conclusion
Systematic imaging processing of LGE-CMR sequences using several SI cut-off ranges may improve and standardize procedure planning to identify VT isthmus sites.
Study context
- Population
- Pigs with established MI and inducible ventricular tachycardia (VT); patients with ischaemic cardiomyopathy undergoing VT ablation18 pigs
- Comparison
- Optimized late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) processing vs 15 signal intensity (SI) cut-off ranges
Main finding
As reported in the abstract
Detection of electrophysiologically defined VT isthmus sites by CMR-based VT corridors
| Group | Specificity | Sensitivity |
|---|---|---|
| 15 SI cut-off ranges | 62% | |
| 7 SI cut-off ranges | 70% | 100% |
Original publication
Novel systematic processing of cardiac magnetic resonance imaging identifies target regions associated with infarct-related ventricular tachycardia. Europace. Published 19 September 2024. doi:10.1093/europace/euae244
Summarised from the published abstract; every number is checked against it