Heart failure & cardiomyopathiesRandomised controlled trial
Nurse-Led Diuretic Titration Via a Point-of-Care Urinary Sodium Sensor in Patients with Acute Decompensated Heart Failure (EASY-HF): A Single-Centre, Randomized, Open-Label Study
- Randomised controlled trial
- single-centre
- open-label
Authors' conclusion
A nurse-led diuretic titration protocol via a point-of-care urinary sodium sensor was feasible, safe and resulted in an increased natriuresis in ADHF compared to SOC.
Study context
- Population
- Patients with acute decompensated HF (mean age 80 ± 8 years, 25% women)
- Participants
- 60 patients
- Comparison
- Nurse-led natriuresis-guided diuretic protocol vs standard of care (SOC)
- Protocolized caren = 30
- SOCn = 30reference
- Primary endpoint
- Natriuresis
- Follow-up
- 48 h
Primary result
As reported in the abstract
P = 0.027
Secondary outcomes
User-friendliness
- Sensor-based protocol evaluated as easy to use by nursing staff and preferred over urinary collections
Safety
Pre-defined safety endpoints
- Similar in both groups
Original publication
Nurse-Led Diuretic Titration Via a Point-of-Care Urinary Sodium Sensor in Patients with Acute Decompensated Heart Failure (EASY-HF): A Single-Centre, Randomized, Open-Label Study. Eur J Heart Fail. Published 14 August 2024. doi:10.1002/ejhf.3429
Summarised from the published abstract; every number is checked against it