Arrhythmias & electrophysiologyCohort study
Occurrence of premature battery depletion in a large multicentre registry of subcutaneous cardioverter-defibrillator patients
- Multicentre registry study
- retrospective
- 9 centres in Europe and the US
Authors' conclusion
This manufacturer-independent analysis highlights a notable incidence of PBD in patients equipped with S-ICD models under advisory, and the rate of PBD in this study corresponds to the rate currently estimated by the manufacturer.
Study context
- Population
- Patients implanted with S-ICD models A209 and A219, October 2012–July 2023
- Participants
- 1,112 S-ICD devices
- Exposure
- S-ICD devices under advisory vs not under advisory
- Under advisoryn = 547
- Outcome
- Incidence of premature battery depletion (PBD; clinically observed sudden drop in battery longevity)
Main finding
As reported in the abstract
Clinically suspected PBD (devices with potentially affected capacitor under FDA advisory) · median follow-up 46 months
Clinically suspected premature battery depletion (PBD)
159 (29.1%)
Observational data: associations, not effects.
Further findings
Time to generator removal or replacement (clinically suspected PBD)
- Median time to generator removal or replacement
- 65 (IQR 55-72) months
Manufacturer confirmation of PBD
- PBD confirmed in devices returned for analysis
- 91.7%
PBD in devices not under advisory
- No cases of PBD
Original publication
Occurrence of premature battery depletion in a large multicentre registry of subcutaneous cardioverter-defibrillator patients. Europace. Published 17 June 2024. doi:10.1093/europace/euae170
Summarised from the published abstract; every number is checked against it