Valvular & structural heart diseaseCohort study
One-Year Outcomes of Screen Failures for Transcatheter Tricuspid Valve Repair: Insights From the TriSelect Study
- retrospective analysis
- registry-based
- 3 tertiary centers in the United States and Germany
Authors' conclusion
In this registry-based analysis, TTVr was associated with improved 1-year survival compared with screen-fail patients, but only when TR was reduced to moderate or less. These findings highlight the critical importance of achieving procedural success with a TTVr along with early referral and transcatheter tricuspid valve intervention device selection.
Study context
- Population
- Patients with severe or greater tricuspid regurgitation evaluated for transcatheter tricuspid valve repair (TTVr) (transcatheter tricuspid valve edge-to-edge repair or direct transcatheter tricuspid valve annuloplasty), TriSelect registry, 2016–2021patients evaluated for TTVr · screen failed 219 · underwent TTVr 318
- Participants
- 547 patients
- Exposure
- TTVr versus screen fail
- TTVrn = 318
- screen failn = 219reference
Main finding
As reported in the abstract
1-year survival (unadjusted Kaplan-Meier) · 1 year
log-rank P <0.001
Observational data: associations, not effects.
Further findings
| Outcome | Values | hazard ratio (95% CI) | P value | |
|---|---|---|---|---|
| 1-year mortality (multivariable Cox) · lower mortality with TTVr · multivariable Cox proportional hazards analysis | 0.40 (0.18–0.86) | P = 0.020 | ||
| 0.20.5125Hazard ratio (log scale) |
| Outcome | Values | Estimate | P value |
|---|---|---|---|
| Survival by residual TR among treated patients · significantly higher with residual TR ≤ moderate | residual TR ≤ moderate 88.0% · residual TR > moderate 69.2% | unadjusted log-rank P =0.005 | |
| Survival, residual TR > moderate vs screen fail · no survival benefit | unadjusted log-rank P =0.74 |
Residual tricuspid regurgitation (TR) ≤ moderate among treated patients
- Treated patients achieving residual TR ≤ moderate
- 224 (70.4%)
Original publication
One-Year Outcomes of Screen Failures for Transcatheter Tricuspid Valve Repair: Insights From the TriSelect Study. Circ Cardiovasc Interv. Published 5 May 2026. doi:10.1161/circinterventions.125.016124
Summarised from the published abstract; every number is checked against it