Optimization Process After Angiography-Guided Stent Implantation: Pre-specified Analysis of the OCCUPI Randomized Trial
Authors' conclusion
Angiography guidance achieved a lower optimization rate than OCT guidance. Furthermore, pre-stenting OCT may facilitate more robust stent expansion.
Study context
- Population
- Patients in the optical coherence tomography (OCT)-guided arm of the OCCUPI trial undergoing PCIfirst consecutive patients in the OCT-guided arm of the OCCUPI trial
- Participants
- 200 patients
- Comparison
- full OCT-guided PCI and angiography-first-guided PCI
Methodological detailsfirst consecutive 200 patients in the OCT-guided arm randomly assigned
- First consecutive 200 patients in the OCT-guided arm randomly assigned
Primary result
As reported in the abstract
Optimization rate (OCT-defined optimization criteria)
P = 0.012
Further findings
- Optimization rate in the angiography-first-guided group after optimization with OCT
- 60.6%
Optimization rate in the angiography-first-guided group after optimization with OCT
- Decrease of maximal malapposition distance and resolution of major edge dissections
Minimal stent area (MSA)
- MSA increased after optimization with OCT in the angiography-first-guided group but remained smaller than that of the full OCT-guided group
Clinical outcomes · 1-year
- The clinical outcomes did not differ between groups
Original publication
Optimization Process After Angiography-Guided Stent Implantation: Pre-specified Analysis of the OCCUPI Randomized Trial. Eur Heart J Cardiovasc Imaging. Published 29 September 2026. doi:10.
Summarised from the published abstract; every number is checked against it