Valvular & structural heart diseaseCohort study

Out-of-Hospital 30-Day Mortality After Mitral TEER

JACC Cardiovasc IntervPublished

  • Registry-based cohort study

Authors' conclusion

Although overall 30-day all-cause mortality after mTEER was low, 2 of 5 deaths occurred out-of-hospital after discharge.

Study context

Population
Patients undergoing mTEER, STS/ACC TVT Registry, January 2014–April 2023
Participants
61,139 patients
Outcome
Out-of-hospital all-cause mortality
Follow-up
30 days

Main finding

As reported in the abstract

Died within 30 days of mTEER

1,813 (3.0%)

Of these, died out-of-hospital after discharge

744 (41.0%)

Median time from discharge to out-of-hospital death, days (Q1-Q3: 5-19)

11

Observational data: associations, not effects.

Secondary outcomes

Out-of-hospital CV mortality · 30 days

CV causes, share of out-of-hospital mortality
63.4%

Factors independently associated with higher 30-day out-of-hospital all-cause and CV mortality

Older age, White race, non-Hispanic ethnicity, lower baseline hemoglobin, poor baseline health status, NSTEMI presentation, lower LVEF, higher acuity presentation, in-hospital complications, ≥moderate residual mitral regurgitation, no ACEi/ARB at discharge

Original publication

Out-of-Hospital 30-Day Mortality After Mitral TEER. JACC Cardiovasc Interv. Published 25 February 2025. doi:10.1016/j.jcin.2025.01.425

Summarised from the published abstract; every number is checked against it