Coronary disease & ACSCase-control study

Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease

Eur Heart JPublished

  • Nationwide case-control study
  • matched (1:10)
  • Mean follow-up 6.5 years (ACHD) and 7.3 years (controls)

Authors' conclusion

This study suggests that survival rates and the incidence of recurrent AMI in ACHD patients are similar to those of controls.

Study context

Population
Adults with a first acute MI, nationwide, 2000–2022matched cohort
Participants
213 vs 2,092
Comparison
ACHD vs matched controls without congenital heart disease
  • ACHDn = 213
  • Controlsn = 2,092reference
Outcome
All-cause mortality and recurrent acute MI

Main finding

As reported in the abstract

All-cause mortality and recurrent AMI · 1 year
  • No significant difference in mortality or recurrent acute myocardial infarction (AMI) rates at 1 year between ACHD and matched controls
  • matched cohort

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
Mortality · 10 years · unadjusted; did not remain after adjustment1.4 (1.0–1.9)

Age before matching · before matching; unmatched n 214 vs 275 377

P < 0.001

Original publication

Outcomes after a first acute myocardial infarction in patients with or without congenital heart disease. Eur Heart J. Published 11 May 2026. doi:10.1093/eurheartj/ehag216

Summarised from the published abstract; every number is checked against it