Arrhythmias & electrophysiologyCohort study
Outcomes of catheter ablation in high-risk patients with Brugada syndrome refusing an implantable cardioverter defibrillator implantation
- Cohort study
Ventricular fibrillation (VF)-triggering PVCs ablated in 3 (16.7%), VF substrates in 15 (83.3%); epicardial ablation in 12 (66.7%)
Authors' conclusion
Catheter ablation is an effective alternative therapy for improving arrhythmic outcomes in patients with symptomatic BrS who decline ICD implantation.
Study context
- Population
- Patients with symptomatic Brugada syndrome
- Participants
- 40 patients
- Exposure
- Catheter ablation (CA) vs implantable cardioverter defibrillator (ICD) implantation
- Outcome
- Composite of:
- VF episodes
- SCD
- Follow-up
- During
Main finding
As reported in the abstract
median follow-up 46.2 (17.5-73.7) months
CA
5.6
%
ICD
54.5%
Log-rank P = 0.012
Observational data: associations, not effects.
Further findings
| Outcome | CA | ICD | P value |
|---|---|---|---|
| Shanghai risk score (baseline) · comparable | 7.05 ± 0.80 | 6.71 ± 0.86 | P = 0.351 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes of catheter ablation in high-risk patients with Brugada syndrome refusing an implantable cardioverter defibrillator implantation. Europace. Published 27 October 2023. doi:10.1093/europace/euad318
Summarised from the published abstract; every number is checked against it