Acute cardiac care & resuscitation
Outcomes of patients with cancer admitted with heart failure–associated cardiogenic shock
Authors' conclusion
Among patients admitted for HF-CS, patients with cancer are at increased risk of in-hospital death, thrombotic complications, and major bleeding compared with patients without cancer. Future studies are needed to guide nuanced evaluation and management of this population to improve outcomes.
Study context
- Population
- Adult patients admitted for heart failure (HF)-related cardiogenic shock (HF-CS) between 2014 and 2020admissions for HF-CS, 7306 (5.3%) had active cancer
- Participants
- 137,316 admissions
- Exposure
- Patients admitted for HF-related cardiogenic shock (HF-CS) with cancer vs. without cancer
- Patients with cancern = 7,306
- Outcome
- In-hospital death, major bleeding, and thrombotic complications
- Follow-up
- In-hospital
Methodological details1 patient with cancer matched to 10 patients without cancer
- 1 patient with cancer matched to 10 patients without cancer
Main finding
As reported in the abstract
patients with cancer vs patients without cancerOdds ratio (95% CI)
In-hospital death
1.12(1.06–1.18)
Thrombotic complications
1.12(1.03–1.21)
Major bleeding
1.23(1.17–1.31)
Observational data: associations, not effects.
Further findings
| Outcome | Patients with cancer | Patients without cancer |
|---|---|---|
| Temporal trends in in-hospital mortality, 2014 to 2020 | Ptrend = 0.43 no significant change | Ptrend < 0.001 decreased mortality over time |
90-day readmission rates among patients who survived initial hospitalization (exploratory)
- Rates of readmission were similar for patients with and without cancer
Original publication
Outcomes of patients with cancer admitted with heart failure–associated cardiogenic shock. Eur Heart J Acute Cardiovasc Care. Published 24 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →