Valvular & structural heart disease
Outcomes of tricuspid transcatheter edge-to-edge repair in subjects with endocardial leads
Authors' conclusion
In the bRIGHT EU PAS, T-TEER using the TriClip system was safe and effective in severe TR subjects with an endocardial lead across the TV.
Study context
- Population
- Subjects with endocardial leads across the tricuspid valve undergoing tricuspid TEER (T-TEER) with the TriClip system in the bRIGHT EU Post-Approval Study (PAS)subjects with an endocardial lead, of 511 enrolled subjects
- Participants
- 110 subjects
- Exposure
- T-TEER in subjects with endocardial leads; safety compared with subjects without leads
- Subjects with endocardial leadsn = 110
- Outcome
- Tricuspid regurgitation (TR) at least partially related to the lead
Methodological details26 sites in Europe, core laboratory echocardiographic assessment
- 26 sites in Europe
- Core laboratory echocardiographic assessment
Main finding
As reported in the abstract
Subjects with endocardial leads
80.7%
Observational data: associations, not effects.
Further findings
| Outcome | Subjects with endocardial leads |
|---|---|
| TR of moderate or less · 30 days | 71% |
| NYHA Functional Class I-II · baseline to 30 days | |
| Baseline | 17% |
| 30 days | 75% |
| Kansas City Cardiomyopathy Questionnaire · baseline to 30 days | mean improvement 20 (SD 24) points |
- NYHA Functional Class I-II — increase from baseline to 30 days
- p<0.0001
- Kansas City Cardiomyopathy Questionnaire — p
- p<0.0001
Original publication
Outcomes of tricuspid transcatheter edge-to-edge repair in subjects with endocardial leads. EuroIntervention. Published 3 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →