Heart failure & cardiomyopathiesResearch article

Pathophysiology and Therapeutic Needs in Nonobstructive Hypertrophic Cardiomyopathy

JACC Heart FailPublished

  • Narrative review

Study context

Population
Nonobstructive hypertrophic cardiomyopathy (HCM)

Main finding

As reported in the abstract

Prevalence and morbidity of nonobstructive HCM

Estimated prevalence of HCM

over 1 in 500 individuals

Share of HCM cases that are nonobstructive

approximately 30% to 70%

Original publication

Pathophysiology and Therapeutic Needs in Nonobstructive Hypertrophic Cardiomyopathy. JACC Heart Fail. Published 24 September 2025. doi:10.1016/j.jchf.2025.102658

Summarised from the published abstract; every number is checked against it