Heart failure & cardiomyopathiesCohort study

Patient Mortality Following New-Onset Heart Failure Stratified by Cancer Type and Status

Eur J Heart FailPublished

  • Nationwide cohort study
  • Danish nationwide registries

Authors' conclusion

Standardized 1-year all-cause mortality was comparable for patients with history of cancer and non-active cancer regardless of cancer type, but varied comprehensively for active cancers. Prognostic impact of age was limited for active lung cancer.

Study context

Population
Danish patients with new-onset heart failure (HF), 2000–2018, with breast, gastrointestinal or lung cancer7.3% with breast, GI or lung cancer
Participants
193,359 patients
Exposure
1-year mortality after new-onset HF by cancer type and status
Outcome
Standardized all-cause mortality (G-computation)
Follow-up
1 year

Main finding

As reported in the abstract

Standardized 1-year all-cause mortality

Observational data: associations, not effects.

Further findings

Age-stratified 1-year all-cause mortality (Kaplan-Meier)

Mortality increased incrementally with age, except for active lung cancer

Baseline characteristics

Patients with cancer older and more comorbid than those without cancer

Original publication

Patient Mortality Following New-Onset Heart Failure Stratified by Cancer Type and Status. Eur J Heart Fail. Published 15 August 2023. doi:10.1002/ejhf.2984

Summarised from the published abstract; every number is checked against it