Heart failure & cardiomyopathiesCohort study
Patient Profiles in Heart Failure with Reduced Ejection Fraction: Prevalence, Characteristics, Treatments and Outcomes in a Real-World Heart Failure Population
- Registry-based cohort study
Authors' conclusion
In a real-world cohort, most patients fit in a few easily identifiable profiles; the nine profiles at highest risk of mortality/morbidity accounted for only 5% of the population.
Study context
- Population
- Patients with HFrEF in the Swedish Heart Failure Registry (SwedeHF), 2013–202193 of 108 profiles identified
- Outcome
- Composite of:
- CV mortality or first HF hospitalization
- By patient profile
Main finding
As reported in the abstract
Nine most frequent profiles (eGFR 30-60 or ≥60 ml/min/1.73 m², systolic blood pressure (sBP) 90-140 mmHg, no hyperkalaemia): share of population
70.5%
Nine profiles with highest event rates (no hyperkalaemia, mostly eGFR <30 ml/min/1.73 m² and atrial fibrillation (AF)): share of population
5%
Observational data: associations, not effects.
Original publication
Patient Profiles in Heart Failure with Reduced Ejection Fraction: Prevalence, Characteristics, Treatments and Outcomes in a Real-World Heart Failure Population. Eur J Heart Fail. Published 29 May 2023. doi:10.1002/ejhf.2892
Summarised from the published abstract; every number is checked against it