Coronary disease & ACSCohort study

Patient-Specific Registration of Segmental Jeopardy and Viability

JACC Cardiovasc ImagingPublished

  • Retrospective cohort study
  • propensity score-adjusted

Authors' conclusion

Patient-specific coronary tree-based reporting to define jeopardized but viable myocardium accurately is clinically feasible and identifies ICM patients who experience lower mortality from early revascularization.

Study context

Population
Patients with ischemic cardiomyopathy (ICM) (obstructive CAD and LVEF <50%) undergoing CMR and invasive coronary angiography, 2015–2022193 early revascularization
Participants
941 patients
Exposure
Early revascularization vs no early revascularization, by jeopardized but viable myocardium
  • Early revascularizationn = 193
Outcome
All-cause mortality
Follow-up
Median 4.8 years

Main finding

As reported in the abstract

Interaction with revascularization for mortality
viable segments × revascularization · no interaction
interaction HR 1.09; P = 0.211
Duke Jeopardy Score × revascularization · no interaction
interaction HR 0.93; P = 0.245
Early revascularization, ≥3 jeopardized but viable segments · mortality
propensity score-adjusted HR 0.55; P = 0.015

Observational data: associations, not effects.

Further findings

OutcomeHRP value
Mortality with ≥3 jeopardized but viable segments (subgroup) · propensity score-adjusted0.55P = 0.015

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Patient-Specific Registration of Segmental Jeopardy and Viability. JACC Cardiovasc Imaging. Published 13 January 2026. doi:10.1016/j.jcmg.2025.11.009

Summarised from the published abstract; every number is checked against it