Heart failure & cardiomyopathies
Patients with Cardiac Amyloidosis are at a Greater Risk of Mortality and Hospital Readmission After Acute Heart Failure
Authors' conclusion
The presence of CA in patients with HF was associated with a three-fold greater risk of death and a two-fold greater risk of all-cause hospital readmission 90 days after discharge.
Study context
- Population
- Patients discharged after acute heart failure (HF), ICREX cohort
- Participants
- 27 vs 135
- Comparison
- HF with cardiac amyloidosis (CA) vs HF without CA
- HF + CA+n = 27
- HF + CA-n = 135reference
- Outcome
- Hospital readmission and death rates
- Follow-up
- 90 days after discharge
Methodological detailsmatched 1:5 by sex and age
- Matched 1:5 by sex and age
Main finding
As reported in the abstract
- Higher death rate, all-cause readmission rate and acute heart failure (AHF) readmission rate with HF + CA+
- Death and readmissions occurred sooner after discharge with HF + CA+
Observational data: associations, not effects.
Further findings
Discharge characteristics
- Higher heart rate with HF + CA+
- P = 0.002
- Higher NT-proBNP with HF + CA+
- P < 0.001
- Lower BP with HF + CA+
- P < 0.001
- Lower weight and BMI with HF + CA+
- P < 0.001
Original publication
Patients with Cardiac Amyloidosis are at a Greater Risk of Mortality and Hospital Readmission After Acute Heart Failure. ESC Heart Fail. Published 13 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →