Coronary disease & ACSCohort study

Percutaneous Coronary Interventions in Patients With Prior Transcatheter Aortic Valve Replacement

JACC AdvPublished

  • retrospective

Authors' conclusion

Despite anatomical challenges posed by transcatheter heart valves, coronary access and PCI post-TAVR are highly successful when appropriate techniques are employed. As TAVR continues to expand to younger patients with longer life expectancy, operator familiarity with coronary access strategies will be essential to optimize post-TAVR care.

Study context

Population
Patients undergoing percutaneous coronary intervention (PCI) after prior TAVRof 2,298 patients undergoing TAVR, total 51 PCI cases
Participants
44 patients
Exposure
balloon-expandable vs self-expanding TAVR
Outcome
Technical success rate of PCI

Main finding

As reported in the abstract

PCI technical success, all procedures
96% (49/51 procedures)

Observational data: associations, not effects.

Further findings

Patient and procedural characteristics

Underwent PCI post-TAVR
44 (1.9%)
Mean age
76 ± 9.01 years
Women
39.2%
Median time-to-PCI post-TAVR
25.92 ± 33.35 months
Indication stable angina
35.3%
ST-segment elevation myocardial infarction
7.8%
non-ST-segment elevation myocardial infarction
39.2%
unstable angina
17.6%
Urgent PCI
64.7%
Femoral access
88.2%
Selective guide catheter coronary engagement possible
86.3%
Guide catheter extension
13.7%
Guidewire airmailing and use of guide extension catheter required
11.8%
Atherectomy
11.7%

Original publication

Percutaneous Coronary Interventions in Patients With Prior Transcatheter Aortic Valve Replacement. JACC Adv. Published 20 January 2026. doi:10.1016/j.jacadv.2025.102567

Summarised from the published abstract; every number is checked against it