Valvular & structural heart diseaseCohort study
Performance of Transcatheter Direct Annuloplasty in Patients With Atrial and Nonatrial Functional Tricuspid Regurgitation
- Multicentre cohort study
- consecutive patients
Authors' conclusion
Direct TTVA effectively reduces TR in both A-FTR, which is a strong and independent predictor of achieving TR ≤II, and NA-FTR.
Study context
- Population
- Patients undergoing transcatheter direct tricuspid valve annuloplasty (transcatheter tricuspid valve annuloplasty (TTVA)) for functional tricuspid regurgitation (TR)
- Participants
- 165 consecutive patients
- Exposure
- Atrial functional tricuspid regurgitation (A-FTR) vs nonatrial functional tricuspid regurgitation (NA-FTR) in patients undergoing TTVA
- A-FTRn = 62
- NA-FTRn = 103reference
Main finding
As reported in the abstract
TR ≤II at discharge · discharge
P = 0.001
- TR grade at discharge significantly reduced vs baseline in both subtypes
- P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| TR ≤II at 30 days, A-FTR phenotype as predictor (multivariate) · multivariate analysis | 5.8 (2.1–16.1) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Mortality · up to 1 year
P = 0.011
HF hospitalization · up to 1 year
P = 0.188
Functional class vs baseline · up to 1 year
- Functional class significantly improved vs baseline in both phenotypes
- P < 0.001
Original publication
Performance of Transcatheter Direct Annuloplasty in Patients With Atrial and Nonatrial Functional Tricuspid Regurgitation. JACC Cardiovasc Interv. Published 24 June 2024. doi:10.1016/j.jcin.2024.04.013
Summarised from the published abstract; every number is checked against it