Meta-analysis
Periprocedural Complications With Balloon Pulmonary Angioplasty
- Systematic review and pooled cohort analysis
Authors' conclusion
Procedure-related complications with BPA, including hemoptysis/vascular injury, lung injury/reperfusion edema, mechanical ventilation, and death, were less common in the second period (2018-2022), compared with first period (2013-2017), likely from refinement in patient and lesion selection and procedural technique over time.
Study context
- Population
- Patients with inoperable, medically refractory chronic thromboembolic pulmonary hypertension undergoing balloon pulmonary angioplasty (BPA)26 articles
- Participants
- 1,714 patients
- Comparison
- BPA complications, 2018-2022 vs 2013-2017
Pooled result
As reported in the abstract
Procedure-related complications · average follow up 7.3 months
| Group | Hemoptysis/vascular injury | Lung injury/reperfusion edema | Invasive mechanical ventilation | Mortality |
|---|---|---|---|---|
| 2013-2017 | 14.1% (474/3,351) | 11.3% (377/3,351) | 0.7% (23/3,195) | 2.0% (13/636) |
| 2018-2022 | 7.7% (233/3,029) | 1.4% (57/3,943) | 0.1% (4/3,062) | 0.8% (8/1,071) |
- 2018-2022 vs 2013-2017: P < 0.01 — hemoptysis/vascular injury
- 2018-2022 vs 2013-2017: P < 0.01 — lung injury/reperfusion edema
- 2018-2022 vs 2013-2017: P < 0.01 — invasive mechanical ventilation
- 2018-2022 vs 2013-2017: P < 0.01 — mortality
Original publication
Periprocedural Complications With Balloon Pulmonary Angioplasty. JACC Cardiovasc Interv. Published 22 March 2023. doi:10.1016/j.jcin.2023.01.361
Summarised from the published abstract; every number is checked against it