Coronary disease & ACSMeta-analysis

Periprocedural myocardial infarction after percutaneous coronary intervention and long-term mortality: a meta-analysis

Eur Heart JPublished

  • Systematic review and meta-analysis
  • random-effect model
  • adjusted effect estimates

Authors' conclusion

All currently available international definitions of PMI are associated with an increased risk of all-cause death after percutaneous coronary intervention.

Study context

Population
Patients undergoing PCI
Participants
109,568 patients · 19 studies
Comparison
Periprocedural myocardial infarction (PMI) vs no PMI after PCI, by Universal Definition of Myocardial Infarction (UDMI), ARC-2 and SCAI definitions
Outcome
All-cause death

Pooled result

As reported in the abstract

All-cause mortality
Hazard ratio (95% CI)
UDMII2 34%
1.61(1.32–1.97)
ARC-2I2 0%
2.07(1.40–3.08)
SCAII2 78%
3.24(2.36–4.44)

Further pooled results

PMI incidence

Incidence of PMI progressively lower across UDMI, ARC-2 and SCAI definitions

Ancillary criteria and prognostic performance

Including ancillary criteria increased prognostic performance in UDMI but not in SCAI

Original publication

Periprocedural myocardial infarction after percutaneous coronary intervention and long-term mortality: a meta-analysis. Eur Heart J. Published 14 May 2024. doi:10.1093/eurheartj/ehae266

Summarised from the published abstract; every number is checked against it