Heart failure & cardiomyopathiesTrial design
Physical rehabilitation for older patients with acute heart failure with preserved ejection fraction (HFpEF) (REHAB-HFpEF) trial: Design and rationale
- multicenter, randomized, single-blind, attention-controlled phase 3 trial
- 22 U.S. health system centers
- event-powered
Study context
- Population
- Patients aged ≥60 years hospitalized for acute HFpEFplanned enrollment, 478 of 880 (66%) enrolled as of 24Feb2027
- Participants
- 880 patients
- Primary endpoint
- combined all-cause rehospitalizations and mortality
- Follow-up
- 6 months
No results yet. This paper sets out the design of a trial; its results are to come.
Further findings
Enrollment status · as of 24Feb2027
- Enrollment ongoing
- 478 of 880 (66%)
Original publication
Physical rehabilitation for older patients with acute HFpEF (REHAB-HFpEF) trial: Design and rationale. Am Heart J. Published 10 March 2026. doi:10.1016/j.ahj.2026.107420
Summarised from the published abstract; every number is checked against it