Acute cardiac care & resuscitation

Poorer survival after out-of-hospital cardiac arrest among cancer patients: a population-based register study

Eur Heart J Acute Cardiovasc CarePublished Retrospective cohort study

Authors' conclusion

Cancer is associated with poorer 30-day survival after OHCA.

Study context

Population
Adults (≥18 years) with out-of-hospital cardiac arrest (OHCA), Swedish Register of Cardiopulmonary Resuscitation2,894 (10%) with cancer
Participants
30,163 adults
Exposure
Cancer vs no previous cancer diagnosis
  • All cancersn = 2,894
Outcome
30-day survival
Follow-up
30 days
Methodological detailspopulation-based, national registries
  • Population-based
  • National registries

Main finding

As reported in the abstract

Each group vs controlsAdjusted odds ratio (CI)
All cancers
0.57(0.49–0.66)
Locoregional cancer
0.68(0.57–0.82)
Metastasized cancer
0.24(0.14–0.40)

Observational data: associations, not effects.

Further findings

Return of spontaneous circulation (ROSC), by cancer stage

Locoregional cancer: no statistically significant difference in ROSC vs controls
Metastasized cancer: poorer chance of ROSC

30-day survival, by cancer site

Lower 30-day survival vs controls for lung, gynaecological and haematological cancers

Original publication

Poorer survival after out-of-hospital cardiac arrest among cancer patients: a population-based register study. Eur Heart J Acute Cardiovasc Care. Published 20 May 2023. doi:10.1093/ehjacc/zuad053

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