Cardio-oncology & otherCohort study

Positive Predictive Value of Universal Cardiovascular Disease Risk Assessment for Pregnant and Postpartum Patients

JACC AdvPublication date not resolved

  • retrospective chart review
  • 4 major health networks in the United States
  • 2020 to 2024

Authors' conclusion

The CMQCC CVD Risk Assessment algorithm effectively identifies pregnant and postpartum patients with previously unrecognized CVD. While the overall predictive value is moderate, the PE findings drive the algorithm's strongest predictive performance.

Study context

Population
Pregnant and postpartum patients undergoing CMQCC cardiovascular disease (CVD) risk assessmentpregnant and postpartum patients assessed with the CMQCC algorithm
Participants
19,238 participants
Exposure
CMQCC CVD risk assessment algorithm against confirmed CVD

Main finding

As reported in the abstract

Identified as "at risk" for CVD

Identified as "at risk" for CVD

2.0%

Observational data: associations, not effects.

Further findings

Subsequently confirmed CVD

Confirmed to have CVD
2.3%

Overall positive predictive value

Positive predictive value
15.6% (95% CI 0.1278-0.1887)

Most predictive elements

Physical exam (PE) findings were the most predictive elements of the risk assessment algorithm

Original publication

Positive Predictive Value of Universal Cardiovascular Disease Risk Assessment for Pregnant and Postpartum Patients. JACC Adv. doi:10.1016/j.jacadv.2026.103069

Summarised from the published abstract; every number is checked against it