Acute cardiac care & resuscitation

Post-Shock Asystole in Patients Dying Out of Hospital While Wearing a Cardioverter Defibrillator

JACC Clin ElectrophysiolPublished Retrospective analysis of the FDA MAUDE database

Authors' conclusion

Post-shock asystole appears to be common in patients who die OOH after being shocked by a WCD for VF or VT. PS-A also occurs after inappropriate WCD shocks for non-VF/VT rhythms. Implanted pacemakers may not prevent PS-A after a WCD shock.

Study context

Population
Patients dying out of hospital (OOH) while wearing a wearable cardioverter-defibrillator (WCD) who received a shock, US FDA MAUDE reports, January 2017 to March 2022
Participants
313 patients
Exposure
Ventricular fibrillation (VF) vs ventricular tachycardia (VT) vs Non-VF/VT
  • VFn = 150
  • VTn = 90
  • Non-VF/VTn = 73
Outcome
Post-shock asystole (PS-A) and post-shock bradycardia (PS-B; <50 beats/min)

Main finding

As reported in the abstract

Post-shock asystole (PS-A)
204 (65.2%)
PS-B
111 (35.5%)
PS-A patients who also had PS-B
85 (41.7%)
PS-A patients with initial shocked rhythm VF or VT
185 (90.7%)
PS-A patients initially inappropriately shocked (AF/SVT n = 7, idioventricular n = 8, sinus n = 4)
19 (9.3%)
PS-A after first WCD shock
118 (63.8%)
PS-A after first, second or third shock
159 (85.9%)

Observational data: associations, not effects.

Further findings

Post-shock heart block

Patients with post-shock heart block
7

Patients with permanent pacemakers

Patients with permanent pacemakers
8
Noncapture and/or asystole after 1 to 4 shocks
7
Pacemaker nonfunctional after 1 shock

Original publication

Post-Shock Asystole in Patients Dying Out of Hospital While Wearing a Cardioverter Defibrillator. JACC Clin Electrophysiol. Published 22 February 2023. doi:10.1016/j.jacep.2022.12.016

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