Valvular & structural heart diseaseCohort study
Post-transcatheter aortic valve implantation isolated PR prolongation: incidence and clinical significance
- Retrospective cohort study
- consecutive patients
Authors' conclusion
Post-TAVI IPRP in patients with narrow QRS is not associated with adverse outcome.
Study context
- Population
- Consecutive TAVI patientsconsecutive TAVI patients reviewed
- Participants
- 1,108 patients
- Exposure
- Isolated PR prolongation vs no post-TAVI electrocardiogram (ECG) changes
- Isolated PR prolongation (IPRP)n = 146
- Controln = 290reference
- Outcome
- PPI and overall mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
| Group | Permanent pacemaker implantation (PPI) | Death |
|---|---|---|
| IPRP | 4 (2.7%) | 10 (6.8%) |
| Control | 7 (2.4%) | 25 (8.6%) |
- IPRP vs Control: P = 0.838 — PPI
- IPRP vs Control: P = 0.521 — mortality
Observational data: associations, not effects.
Further findings
PPI, wide QRS (subgroup)
P = 0.126
| Outcome | IPRP | Control | P value |
|---|---|---|---|
| PPI, narrow QRS (subgroup) · 1 year · all deaths non-cardiac except one unknown cause | 0 events | Not reported in the abstract |
Combined PPI and mortality (multivariate Cox)
- Narrow QRS: neither PR prolongation nor baseline or maximal PR interval associated
- Wide QRS: baseline PR interval and QRS width associated, PR prolongation not
Original publication
Post-transcatheter aortic valve implantation isolated PR prolongation: incidence and clinical significance. Europace. Published 16 January 2024. doi:10.1093/europace/euae011
Summarised from the published abstract; every number is checked against it