Coronary disease & ACS

Postdilation Strategies Following Provisional Stenting of Left Main Coronary Bifurcations

JACC AdvPublished

  • validated computational simulations
  • patient-specific
  • reconstructed in three dimensions and virtually stented
+2 more
  • patient-specific
  • reconstructed in three dimensions and virtually stented

Authors' conclusion

KBI is superior to P or P-S-P. Combined high-pressure sequential and nominal-pressure simultaneous KBI outperforms sequential or simultaneous KBI alone, particularly in stiff calcified or fibrous lesions. Final POT after KBI provides no incremental advantage.

Study context

Population
Patient-specific left main (LM) bifurcations treated with provisional stenting
Participants
Four patient-specific LM bifurcations
Comparison
Techniques were compared based on lumen/stent morphology and hemodynamics.

Main finding

As reported in the abstract

Overall ranking of P vs other techniques (left circumflex ostium)

Overall ranking of P vs other techniques: smaller ostial area with P compared with other techniques

27%

larger area exposed to high wall shear stress gradient at the left circumflex ostium with P compared with other techniques

76%

Further findings

P-S-P ranking (left anterior descending artery ostium)

greater area exposed to high relative residence time at the left anterior descending artery ostium with P-S-P
29%
P-S-P ranked second lowest
P-S-P ranking: 14% smaller ostial area and 29% greater area exposed to high relative residence time at the left anterior descending artery ostium

Techniques incorporating kissing balloon inflation (KBI)

Techniques incorporating KBI showed the most favorable performance, with combined sequential and simultaneous KBI performing best, particularly in calcified or fibrous plaques

Final proximal optimization technique (POT) after KBI

Final POT after KBI did not confer incremental benefit

Original publication

Postdilation Strategies Following Provisional Stenting of Left Main Coronary Bifurcations. JACC Adv. Published 27 April 2026. doi:10.1016/j.jacadv.2026.102750

Summarised from the published abstract; every number is checked against it