Arrhythmias & electrophysiologyCohort study

Posterior wall ablation by pulsed-field ablation: procedural safety, efficacy, and findings on redo procedures

EuropacePublished

  • Observational cohort study
  • consecutive patients

Authors' conclusion

Posterior wall ablation with this pentaspline PFA catheter can be safely and efficiently performed with a high durability observed during redo procedures.

Study context

Population
Patients undergoing posterior wall ablation by pulsed-field ablation (recurrent AF despite durable pulmonary vein isolation or roof-dependent atrial tachycardia)67% redo procedures
Participants
215 patients

Main finding

As reported in the abstract

Acute PWA success (single-group); arrhythmia-free outcome

Posterior wall ablation (PWA) successful in all patients

100%

Pulsed-field ablation (PFA) lesions applied, median (IQR 32-44)

36

One-year arrhythmia-free outcome (Kaplan-Meier)

53%

Observational data: associations, not effects.

Further findings

OutcomeValues
Lesion durability at redo procedure · median 6.9 (IQR 2.4-11) monthsRedo 12% · Durable PWA 22 (85%)
Lesion durability at redo procedure — Roof-dependent atrial tachycardia (AT) among 4 with posterior wall reconnection
3 (75%)

Safety

Severe adverse events

Cardiac tamponade
1 (0.9%)
Vascular access complication
1 (0.9%)

Original publication

Posterior wall ablation by pulsed-field ablation: procedural safety, efficacy, and findings on redo procedures. Europace. Published 16 January 2024. doi:10.1093/europace/euae006

Summarised from the published abstract; every number is checked against it