HypertensionCohort study

Postpartum Ambulatory Blood Pressure Patterns Following New-Onset Hypertensive Disorders of Pregnancy

JAMA CardiolPublished

  • Cohort study
  • population-based
  • single referral hospital remote blood pressure (BP) monitoring program

Authors' conclusion

This cohort study found that more than 80% of individuals with hypertensive disorders of pregnancy had ongoing hypertension after hospital discharge, with approximately 14% developing severe hypertension.

Study context

Population
Individuals with new-onset hypertensive disorder of pregnancy (preeclampsia or gestational hypertension), no prepregnancy hypertension, delivered September 2019–June 2021, enrolled in a remote postpartum BP monitoring program
Participants
2,705 individuals
Exposure
Severe hypertension vs BP normalization after postpartum discharge
  • Severe hypertensionn = 382
Outcome
Readmission and ED visits
Follow-up
Within the first 6 weeks post partum

Main finding

As reported in the abstract

6 weeks post partum
Severe hypertension vs BP normalizationAdjusted odds ratio (95% CI)
ED visits
1.85(1.17–2.92)
hospital readmissions
6.75(3.43–13.29)

Observational data: associations, not effects.

Further findings

Postdischarge BP course

Persistent hypertension after discharge
2214 (81.8%)
Severe hypertension after discharge
382 (14.1%)
Antihypertensive medication initiated after discharge
610 (22.6%)

Postdischarge home BP trajectories by inpatient BP category

Significant overlap between inpatient SBP ≥140 to 149 mm Hg and/or DBP ≥90 to 99 mm Hg and SBP ≥150 mm Hg and/or DBP ≥100 mm Hg

Original publication

Postpartum Ambulatory Blood Pressure Patterns Following New-Onset Hypertensive Disorders of Pregnancy. JAMA Cardiol. Published 1 August 2024. doi:10.1001/jamacardio.2024.1389

Summarised from the published abstract; every number is checked against it