Arrhythmias & electrophysiology
Practical Approaches to Coronary Venous Ethanol Ablation for Refractory Ventricular Arrhythmias: Technique Selection and Clinical Outcomes
Authors' conclusion
In patients with VAs refractory to endocardial RFA, CVEA was associated with favorable acute and long-term outcomes, with no fatal complications. Technique selection should be tailored to the venous anatomy, with judicious ethanol volume adjustment.
Study context
- Population
- Patients with ventricular arrhythmias refractory to endocardial RFAunderwent coronary venous ethanol ablation (CVEA), of 204 consecutive patients undergoing VA ablation, 55 had ventricular arrhythmias (VAs) refractory to endocardial RFA · premature ventricular contraction (PVC) 33 · ventricular tachycardia (VT) 9
- Participants
- 42 patients
- Comparison
- PVC vs VT
- PVCn = 33
- VTn = 9
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Acute success
PVC
32/33
events
VT
all patients
events
Further findings
Events
| Outcome | PVC | VT |
|---|---|---|
| Long-term success · median follow-up of 1,024 days | 22 | 5 |
Intraprocedural findings and long-term recurrence
- No association was observed between intraprocedural findings and long-term recurrence
Exploratory analyses: technique and ethanol volume
- Favorable outcomes for the modified double-balloon technique in anatomically selected cases
- Association between higher ethanol volume and ethanol-related complications
- Exploratory
Safety
CVEA-related procedural complications
- Patients with CVEA-related procedural complications
- 13
- No fatal events reported
Original publication
Practical Approaches to Coronary Venous Ethanol Ablation for Refractory Ventricular Arrhythmias: Technique Selection and Clinical Outcomes. Heart Rhythm. Published 16 October 2026. doi:10. 1016/ j. hrthm. 2026. 10. 012
Summarised from the published abstract; every number is checked against it