Arrhythmias & electrophysiology

Practical Approaches to Coronary Venous Ethanol Ablation for Refractory Ventricular Arrhythmias: Technique Selection and Clinical Outcomes

Heart RhythmPublished Consecutive patients undergoing VA ablation at our center

Authors' conclusion

In patients with VAs refractory to endocardial RFA, CVEA was associated with favorable acute and long-term outcomes, with no fatal complications. Technique selection should be tailored to the venous anatomy, with judicious ethanol volume adjustment.

Study context

Population
Patients with ventricular arrhythmias refractory to endocardial RFAunderwent coronary venous ethanol ablation (CVEA), of 204 consecutive patients undergoing VA ablation, 55 had ventricular arrhythmias (VAs) refractory to endocardial RFA · premature ventricular contraction (PVC) 33 · ventricular tachycardia (VT) 9
Participants
42 patients
Comparison
PVC vs VT
  • PVCn = 33
  • VTn = 9
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Acute success

PVC

32/33

events

VT

all patients

events

Further findings

Events

OutcomePVCVT
Long-term success · median follow-up of 1,024 days225

Intraprocedural findings and long-term recurrence

No association was observed between intraprocedural findings and long-term recurrence

Exploratory analyses: technique and ethanol volume

Favorable outcomes for the modified double-balloon technique in anatomically selected cases
Association between higher ethanol volume and ethanol-related complications
  • Exploratory

Safety

CVEA-related procedural complications

Patients with CVEA-related procedural complications
13
No fatal events reported

Original publication

Practical Approaches to Coronary Venous Ethanol Ablation for Refractory Ventricular Arrhythmias: Technique Selection and Clinical Outcomes. Heart Rhythm. Published 16 October 2026. doi:10.1016/j.hrthm.2026.10.012

Summarised from the published abstract; every number is checked against it

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