Pre–Heart Failure Longitudinal Change in a Hispanic/Latino Population-Based Study: Insights From the Echocardiographic Study of Latinos

Kuno, T; Vasquez, N; April-Sanders, AK; Swett, K; Kizer, JR; Thyagarajan, B; Talavera, GA; Ponce, SG; Shook-Sa, BE; Penedo, FJ; Daviglus, ML; Kansal, MM; Cai, J; Kitzman, D; Rodriguez, CJ

doi:10.1016/j.jchf.2023.04.008

Heart failure & cardiomyopathies

Pre–Heart Failure Longitudinal Change in a Hispanic/Latino Population-Based Study: Insights From the Echocardiographic Study of Latinos

JACC Heart FailPublished 17 May 2023Prospective cohort study

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Authors' conclusion

Hispanics/Latinos exhibited significant worsening of pre-HF characteristics over time. Prevalence and incidence of pre-HF are high and are associated with increasing HF risk factor burden and with incidence of cardiac events.

Study context

Population: Hispanics/Latinos in the Echo-SOL study, echocardiography at baseline and 4.3 years later
Participants: 1,643 participants

Outcome: Pre-HF prevalence and incidence (any abnormal cardiac parameter: LVEF <50%, absolute GLS <15%, grade ≥1 diastolic dysfunction, LV mass index >115 g/m² men / >95 g/m² women, or relative wall thickness >0.42)
Follow-up: 4.3 years

Methodological detailspopulation-based, sampling weights and survey statistics

Population-based
Sampling weights and survey statistics

Main finding

As reported in the abstract

Pre-HF

Prevalence of pre-heart failure (pre-HF) at baseline

66.7%

Incidence of pre-HF during follow-up

66.3%

Observational data: associations, not effects.

Further findings

Prevalent and incident pre-HF by heart failure (HF) risk factor number

	← Lower odds ←→ Higher odds →	Adjusted OR (95% CI)
Increasing the number of HF risk factorsPrevalence of pre-HF	0.512	1.36 (1.16–1.58)
Increasing the number of HF risk factorsIncidence of pre-HF	0.512	1.29 (1.00–1.68)
	0.512Adjusted odds ratio (log scale)

Incident clinical HF by prevalent pre-HF

	← Lower risk ←→ Higher risk →	HR (95% CI)
Prevalent pre-HF	0.050.21520	10.9 (2.1–56.3)
	0.050.21520Hazard ratio (log scale)

Cardiac parameters, baseline to follow-up · 4.3 years

Significant worsening of all cardiac parameters except LVEF: all P < 0.01

Original publication

Pre–Heart Failure Longitudinal Change in a Hispanic/Latino Population-Based Study: Insights From the Echocardiographic Study of Latinos. JACC Heart Fail. Published 17 May 2023. doi:10.1016/j.jchf.2023.04.008

Read the original article ↗

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