Heart failure & cardiomyopathiesCohort study
Pre–Heart Failure Longitudinal Change in a Hispanic/Latino Population-Based Study
- Prospective cohort study
- population-based
- sampling weights and survey statistics
Authors' conclusion
Hispanics/Latinos exhibited significant worsening of pre-HF characteristics over time. Prevalence and incidence of pre-HF are high and are associated with increasing HF risk factor burden and with incidence of cardiac events.
Study context
- Population
- Hispanics/Latinos in the Echo-SOL study, echocardiography at baseline and 4.3 years later
- Participants
- 1,643 participants
- Outcome
- Pre-HF prevalence and incidence (any abnormal cardiac parameter: LVEF <50%, absolute GLS <15%, grade ≥1 diastolic dysfunction, LV mass index >115 g/m² men / >95 g/m² women, or relative wall thickness >0.42)
- Follow-up
- 4.3 years
Main finding
As reported in the abstract
Pre-HF
Prevalence of pre-heart failure (pre-HF) at baseline
66.7%
Incidence of pre-HF during follow-up
66.3%
Observational data: associations, not effects.
Further findings
Prevalent and incident pre-HF by heart failure (HF) risk factor number
| Comparison | adjusted OR (95% CI) | |
|---|---|---|
| increasing the number of HF risk factors · prevalence of pre-HF | 1.36 (1.16–1.58) | |
| increasing the number of HF risk factors · incidence of pre-HF | 1.29 (1.00–1.68) | |
| 0.512Adjusted odds ratio (log scale) |
Incident clinical HF by prevalent pre-HF
| Comparison | HR (95% CI) | |
|---|---|---|
| Prevalent pre-HF | 10.9 (2.1–56.3) | |
| 0.050.21520Hazard ratio (log scale) |
Cardiac parameters, baseline to follow-up · 4.3 years
- Significant worsening of all cardiac parameters except LVEF
- all P < 0.01
Original publication
Pre–Heart Failure Longitudinal Change in a Hispanic/Latino Population-Based Study. JACC Heart Fail. Published 17 May 2023. doi:10.1016/j.jchf.2023.04.008
Summarised from the published abstract; every number is checked against it