Arrhythmias & electrophysiology

Preceding Night Sleep Quality and Atrial Fibrillation Episodes in the I-STOP-AFIB Randomized Trial

JACC Clin ElectrophysiolPublished Secondary analysis of the I-STOP-AFIB randomised trial

Primary result · Self-reported AF episode next day, per worse sleep qualityResult — go to the resultOdds ratio 1.15 95% CI 1.10–1.20

Authors' conclusion

Poor sleep was associated with an immediately heightened risk for self-reported AF episodes, and a dose-response relationship existed such that progressively worse sleep was associated with longer episodes of AF the next day.

Study context

Population
Patients with symptomatic paroxysmal atrial fibrillation (AF)15,755 days of data
Participants
419 patients
Comparison
Worse vs better preceding-night sleep quality
Primary endpoint
Self-reported AF episode the next day

Primary result

As reported in the abstract

Self-reported AF episode next day, per worse sleep quality

Odds ratio

1.15

95% CI 1.10–1.20

P < 0.0001

Worse sleep quality
OR 1.15 (95% CI 1.10–1.20); P < 0.0001

Per worse sleep quality, as printed

Further findings

Mobile ECG-confirmed AF events · next day

OR (95% CI)P value
Worse sleep quality1.04 (0.95–1.13)P = 0.43
OutcomeDifference (more minutes of AF) (95% CI)P value
Duration of self-reported AF episodes · next day16 (12–21)P < 0.001
  • Mobile ECG-confirmed AF events: substantially fewer mobile ECG-confirmed events may have limited statistical power

Original publication

Preceding Night Sleep Quality and Atrial Fibrillation Episodes in the I-STOP-AFIB Randomized Trial. JACC Clin Electrophysiol. Published 1 November 2023. doi:10.1016/j.jacep.2023.09.009

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.