Cardio-oncology & otherCohort study

Predicting Long-Term Clinical Outcomes of Patients With Recurrent Pericarditis

J Am Coll CardiolPublished

  • Retrospective cohort study
  • prognostic model development
  • machine learning survival models
  • consecutive patients

Authors' conclusion

We developed a novel risk-stratification model for predicting CR in RP. Our model can also aid in stratifying patients, with high discriminative ability.

Study context

Population
Patients with recurrent pericarditis, 2012–2019
Participants
365 consecutive patients
Outcome
Clinical remission (cessation of all anti-inflammatory therapy with complete resolution of symptoms)
Follow-up
Within 5 years

Main finding

As reported in the abstract

Prediction of clinical remission

Clinical remission (CR) achieved

118 (32%)

Model C-index on test set

0.800

Stratification into low-, intermediate- and high-risk groups (log-rank test)

P < 0.0001

Observational data: associations, not effects.

Original publication

Predicting Long-Term Clinical Outcomes of Patients With Recurrent Pericarditis. J Am Coll Cardiol. Published 31 August 2024. doi:10.1016/j.jacc.2024.05.072

Summarised from the published abstract; every number is checked against it