Arrhythmias & electrophysiology
Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study
Authors' conclusion
A multimodal pulmonary vein catheterization assessment determined angiographic and intravascular ultrasound findings to be the most predictive of 12-month pulmonary vein outcome.
Study context
- Population
- Patients under 13 years of age undergoing cardiac catheterization for pediatric intraluminal pulmonary vein stenosis (PVS)patients, 200 veins by angiography · angiography (veins) 200 · pressure assessment 171 · intravascular ultrasound 169 · balloon compliance testing 58 · wall shear stress calculations 141
- Participants
- 50 participants
- Exposure
- Multimodal catheterization characteristics (angiography, pulmonary vein pressure, intravascular ultrasound, balloon compliance testing, wall shear stress) and their association with vein outcomes
- Outcome
- Worse vein outcome (vein status assigned by an end point committee)
- Follow-up
- 12 months
Methodological detailsstandardized catheterization assessment
- Standardized catheterization assessment
Main finding
As reported in the abstract
Odds ratio (95% CI)P value
Angiographic upstream luminal narrowing
3.26(1.38–7.7)
P = 0.007Ostial diameter <6 mm
3.93(1.29–12)
P = 0.016≥35% upstream wall thickness by intravascular ultrasound
5.05(2.03–12.5)
P < 0.001Observational data: associations, not effects.
Secondary outcomes
Transplant-free survival (secondary outcome) · 12 months
- Transplant-free survival
- 92%
Original publication
Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study. Circ Cardiovasc Interv. Published 14 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →