Coronary disease & ACS

Predicting Temporal Trends and Hospital-Level Variation in Calcium Modification Strategies Adoption in Percutaneous Coronary Intervention

JACC AdvPublished Simulation modelling study of registry data

Authors' conclusion

This analysis demonstrates divergent adoption patterns between IVL and CA, with IVL showing more rapid uptake.

Study context

Population
PCI in US registries, 2009–2022100,000 simulated iterations
Exposure
Intravascular lithotripsy (IVL) vs coronary atherectomy (CA)
Outcome
Predicted utilization of calcium modification strategies
Follow-up
2035
Methodological detailsMonte Carlo simulations, logistic growth models, multiple US registries
  • Monte Carlo simulations
  • Logistic growth models
  • Multiple US registries

Main finding

As reported in the abstract

Projected adoption
GroupValueMean annual growth
IVL32.41% (95% CI 28.76%–36.06%)2.5% (95% CI: 2.1% to 2.9%)
CA4.5 to 5.5% (10% to 90% CI 3.8%–6.2%)

Value

IVL32.41% (95% CI 28.76%–36.06%)
CA4.5 to 5.5% (10% to 90% CI 3.8%–6.2%)

Mean annual growth

IVL2.5% (95% CI: 2.1% to 2.9%)
CA— not stated in the abstract

Observational data: associations, not effects.

Further findings

Hospital-level variation: high-volume centres (>10% CA use) · 2020 to 2035

Increasing variability; high-volume centres increased from 8.6% (2020) to 29.6% (2035)
8.6% to 29.6%

Original publication

Predicting Temporal Trends and Hospital-Level Variation in Calcium Modification Strategies Adoption in Percutaneous Coronary Intervention. JACC Adv. Published 7 October 2025. doi:10.1016/j.jacadv.2025.102159

Composed by AI from the published abstract and checked against it. How Briefs are made →

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