Valvular & structural heart diseaseCohort study
Prediction of Mortality and Heart Failure Hospitalization After Transcatheter Tricuspid Valve Interventions
- Registry-based cohort study
- multicenter
- multinational
Authors' conclusion
In the TriValve registry, the TRI-SCORE has a suboptimal performance in predicting clinical outcomes. However, a TRISCORE ≥8 is associated with an increased risk of clinical events and a lack of prognostic benefit after successful TTVI.
Study context
- Population
- Patients undergoing transcatheter tricuspid valve intervention (TTVI), TriValve registry
- Participants
- 634 patients
- Exposure
- TRI-SCORE tertiles
- TRI-SCORE 0–5n = 223reference
- TRI-SCORE 6–7n = 221
- TRI-SCORE ≥8n = 190
- Outcome
- All-cause death; all-cause death or HF hospitalization
- Follow-up
- Median 186 days
Main finding
As reported in the abstract
TRI-SCORE ≥8 vs TRI-SCORE 0–5Estimate (95% CI)
30-day all-cause mortality
OR 3.00(1.38–6.55)
all-cause mortality, median follow-up 186 days
HR 2.17(1.78–4.13)
all-cause death or HF hospitalization, median follow-up 186 days
HR 2.08(1.57–2.74)
Observational data: associations, not effects.
Further findings
Postprocedure length of stay
- Increased with a TRI-SCORE increase
NYHA functional class
- Improved across all TRI-SCORE values
Original publication
Prediction of Mortality and Heart Failure Hospitalization After Transcatheter Tricuspid Valve Interventions. JACC Cardiovasc Interv. Published 8 April 2024. doi:10.1016/j.jcin.2024.02.013
Summarised from the published abstract; every number is checked against it