Arrhythmias & electrophysiology
Predictors of left atrial appendage emptying velocity: Derivation and validation of CHIRP3(M-1) score
Authors' conclusion
We developed and validated a novel risk stratification system to predict reduced LAAev using clinical and echocardiographic variables.
Study context
- Population
- Patients undergoing transesophageal echocardiogram (TEE) (history of atrial fibrillation (AF) 82.1%)derivation n = 695, validation n = 300
- Participants
- 995 patients
- Exposure
- Low and high vs intermediate CHIRP3M-1 scores
- Outcome
- Left atrial appendage emptying velocity (LAAev) <30 cm/s
Methodological detailssingle-centre, derivation and validation sets
- Single-centre
- Derivation and validation sets
Main finding
As reported in the abstract
LAAev <30 cm/s (validation set)
Each group vs intermediate scoresOdds ratio (95% CI)P value
Low scores
0.41(0.21–0.78)
P = 0.007High scores
2.58(1.45–4.61)
P = 0.001Observational data: associations, not effects.
Original publication
Predictors of left atrial appendage emptying velocity: Derivation and validation of CHIRP3(M-1) score. Heart Rhythm. Published 5 October 2024. doi:10.
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