Valvular & structural heart disease

Predictors of Length-of-Stay Among Transcatheter Aortic Valve Replacement Patients Using a Supervised Machine Learning Algorithm

JACC AdvPublished Supervised random forest machine learning (ML) algorithms

Authors' conclusion

ML algorithms may have an important role in identifying novel predictors of short and prolonged length of stay following TAVR. These efforts may facilitate targeted quality improvement programs to decrease length of stay post-TAVR.

Study context

Population
Outpatient transcatheter aortic valve replacement (TAVR) procedures, Biome data set, United States, 2017–2021outpatient TAVR procedures from 21 centers
Participants
9,172 procedures
Comparison
ML models compared to standard multivariable models in predicting LOS
Methodological details21 centers, 70% development sample, 30% test sample
  • 21 centers
  • 70% development sample, 30% test sample

Main finding

As reported in the abstract

Important predictors identified

Variables included as important predictors for the short length of stay (SLOS) model

Twenty

Variables included as important predictors for the long length of stay (LLOS) model

22

Further findings

OutcomeSLOS ML modelLLOS ML modelStandard multivariable model
Predictive power of ML models vs standard multivariable model · ML models more robust than the standard multivariable model
Sensitivity0.810.45Not reported in the abstractStandard multivariable model: not reported in the abstract
Specificity0.700.94Not reported in the abstractStandard multivariable model: not reported in the abstract
AUC0.820.85Not reported in the abstractStandard multivariable model: not reported in the abstract
SLOS AUCNot reported in the abstractNot reported in the abstract0.65SLOS ML model, LLOS ML model: not reported in the abstract
LLOS AUCNot reported in the abstractNot reported in the abstract0.65SLOS ML model, LLOS ML model: not reported in the abstract

Previously unreported predictors

Procedural duration, postprocedure physical therapy, and procedure day of the week

Original publication

Predictors of Length-of-Stay Among Transcatheter Aortic Valve Replacement Patients Using a Supervised Machine Learning Algorithm. JACC Adv. Published 24 June 2025. doi:10.1016/j.jacadv.2025.101902

Summarised from the published abstract; every number is checked against it

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