Valvular & structural heart diseaseCohort study
Predictors of Outcomes of Reintervention After Transcatheter Aortic Valve Replacement
- Registry-based cohort study
- FRANCE 2 and FRANCE TAVI registries
- competing-risk analysis (all-cause death)
Authors' conclusion
Reintervention after TAVR remains rare and was mostly performed early after the procedure and by redo TAVR.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR) 2010–2022 in the FRANCE 2 and FRANCE TAVI registries; reintervention for infective endocarditis excluded
- Participants
- 72,850 patients
- Exposure
- Redo TAVR vs Explant TAVR
- Redo TAVRn = 591
- Explant TAVRn = 111
- Outcome
- Cumulative incidence of reintervention (surgical or transcatheter) after TAVR
- Follow-up
- 8 years
Main finding
As reported in the abstract
Cumulative incidence of overall reintervention
Overall reintervention
1.7%
Redo TAVR
591 patients
Explant TAVR
111 patients
Early reintervention (≤1 year)
62.1% of cases
Observational data: associations, not effects.
Further findings
Mortality, early vs late reintervention · 6 years
P = 0.77
Predictors of reintervention
- Age, mean aortic gradient before TAVR, mean aortic gradient >20 mm Hg, aortic regurgitation ≥ grade 2 and PCI after TAVR predictive of reintervention
Original publication
Predictors of Outcomes of Reintervention After Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. Published 11 March 2025. doi:10.1016/j.jacc.2024.11.048
Summarised from the published abstract; every number is checked against it