Congenital heart diseaseResearch article
Preoperative atrial electrophysiology in pediatric tetralogy of Fallot compared with ventricular septal defect
- Intraoperative epicardial mapping study
Authors' conclusion
Pediatric patients with TOF have more atrial electrophysiological abnormalities, particularly at the LA and PV, than patients with VSD, suggesting that atrial electrophysiological alterations at these sites are more pronounced in patients with TOF.
Study context
- Population
- Pediatric patients with tetralogy of Fallot (TOF) and those with ventricular septal defect (VSD)TOF 26 · VSD 41
- Participants
- 26 vs 41
- Comparison
- preoperative atrial electrophysiology between pediatric patients with TOF and those with VSD
- TOFn = 26
- VSDn = 41
Main finding
As reported in the abstract
Prevalence of LA dilatation
P = 0.004
Further findings
| Outcome | TOF | VSD | P value |
|---|---|---|---|
| Potential voltages · lower in TOF | |||
| LA | 3.4 ± 1.7 mV | 5.3 ± 2.5 mV | |
| PV | 1.8 [1.1-5.6] mV | 4.7 [1.4-8.9] mV | |
| Low-voltage areas · more in TOF | |||
| LA | 12.9% [0.0%-53.7%] | 4.4% [0.0%-29.0%] | |
| PV | 23.9% [3.6%-47.0%] | 7.0% [0.0%-35.9%] | |
| Conduction block (LA) · higher prevalence in TOF | 0.6% [0.0%-6.5%] | 0.0% [0.0%-1.2%] | P < 0.001 |
| Short double potentials (LA) · higher in TOF | 12.1% [0.5%-41.8%] | 8.8% [1.3%-18.9%] | P = 0.032 |
| Long double potentials (LA) · higher in TOF | 0.1% [0.0%-13.8%] | 0.0% [0.0%-2.2%] | P = 0.034 |
- Potential voltages: both P < .01
- Low-voltage areas: both P < .01
Original publication
Preoperative atrial electrophysiology in pediatric tetralogy of Fallot compared with ventricular septal defect. Heart Rhythm. Published 3 September 2026. doi:10.1016/j.hrthm.2026.08.052
Summarised from the published abstract; every number is checked against it