Heart failure & cardiomyopathies

Prevalence and prognostic impact of subclinical venous congestion in patients hospitalized for acute heart failure

Eur Heart J Acute Cardiovasc CarePublished two-centre, prospective observational study

Authors' conclusion

Clinical and subclinical congestion decreased during hospitalisation but worsened shortly after discharge. A quarter of patients had residual venous congestion, which was associated with a worse prognosis at 6 months.

Study context

Population
Patients admitted for heart failure (HF) between June 2021 and March 2023patients included (62% male, mean age 75 ± 15 years)
Participants
120 patients
Exposure
Subclinical venous congestion vs Overt clinical congestion

Main finding

As reported in the abstract

Congestion parameters · during hospitalisation and at the first outpatient visit
  • Congestion parameters decreased during hospitalisation but tended to worsen at the first outpatient visit

Observational data: associations, not effects.

Further findings

Composite endpoint of death from any cause, HF readmissions, or unscheduled visits requiring intravenous diuretic administration · 6-month follow-up

ComparisonHR (95% CI)P value
Subclinical venous congestion · independent predictor2.84 (1.01–8.01)P = 0.048
  • Composite endpoint of death from any cause, HF readmissions, or unscheduled visits requiring intravenous diuretic administration: after adjustment for age, chronic kidney disease, NYHA class at admission, and NT-proBNP level at discharge

Subclinical venous congestion · At discharge

Showed subclinical venous congestion
24%

Adverse outcomes

Subclinical venous congestion group had a significantly higher incidence of adverse outcomes, comparable to those with overt clinical congestion

Original publication

Prevalence and prognostic impact of subclinical venous congestion in patients hospitalized for acute heart failure. Eur Heart J Acute Cardiovasc Care. Published 23 July 2025. doi:10.1093/ehjacc/zuaf097

Summarised from the published abstract; every number is checked against it

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