Coronary disease & ACSCohort study

Prevalence and prognostic importance of chronic kidney disease in patients with coronary heart disease: results from the combined EUROASPIRE IV and V studies

Eur J Prev CardiolPublished

  • Prospective cohort study
  • combined EUROASPIRE IV and V

Authors' conclusion

CKD is common among people with CHD and constitutes an independent risk factor for recurrent CVD events.

Study context

Population
Patients with established coronary heart disease (CHD)9,872 with follow-up
Participants
10,349 patients
Exposure
Chronic kidney disease (CKD) risk categories
Outcome
Time to first CV death, non-fatal MI, stroke, HF hospitalization, bypass surgery or PCI
Follow-up
Median 1.6 years

Main finding

As reported in the abstract

Primary endpoint
adjusted for CV risk factors
Each group vs low riskHazard ratio (95% CI)P value
Moderate risk
1.39(1.19–1.63)
P < 0.0001
High risk
1.75(1.44–2.12)
P < 0001

Observational data: associations, not effects.

Further findings

CKD prevalence (eGFR and urinary albumin/creatinine ratio (UACR))

CKD
27.3%
Low or moderate risk
18.2%
High or very high risk
9.1%
Not diagnosed without UACR
48.9%

Original publication

Prevalence and prognostic importance of chronic kidney disease in patients with coronary heart disease: results from the combined EUROASPIRE IV and V studies. Eur J Prev Cardiol. Published 29 August 2025. doi:10.1093/eurjpc/zwaf528

Summarised from the published abstract; every number is checked against it