Heart failure & cardiomyopathies
Prevalence of arrhythmia-induced cardiomyopathy: A systematic review and meta-analysis
Authors' conclusion
AiCM is the most frequent etiology of LVSD in patients with arrhythmias.
Study context
- Population
- Patients with sustained cardiac arrhythmias across various populations
- Participants
- 7,331 patients26 studies
- Outcome
- Prevalence of arrhythmia-induced cardiomyopathy (AiCM)
Methodological detailsmeta-regression
- Meta-regression
Pooled result
As reported in the abstract
AiCM prevalence
Overall prevalence of arrhythmia-induced cardiomyopathy (AiCM)
8%
Prevalence in cohorts with LV systolic dysfunction
59%
Further pooled results
Factors associated with AiCM prevalence (multivariable meta-regression)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Mean left ventricular ejection fraction | 0.94 (0.90–0.98) | P = 0.002 | |
| Patient age | 1.15 (1.02–1.30) | P = 0.03 | |
| 0.512Odds ratio (log scale) |
| Outcome | SMD (CI) | P value | |
|---|---|---|---|
| Baseline heart rate, AiCMvs controlsRandom effects model; higher in AiCM | 0.35 (0.09–0.61) | P = 0.01 | |
| −0.500.51Difference (linear scale) |
Prevalence in cohorts with left ventricular systolic dysfunction (LVSD) (subgroup)
- AiCM prevalence in LVSD cohorts
- 59%
Original publication
Prevalence of arrhythmia-induced cardiomyopathy: A systematic review and meta-analysis. Heart Rhythm. Published 4 December 2025. doi:10.
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