Heart failure & cardiomyopathiesTrial design
Proactive Heart Failure Screening in Obesity: Design, Recruitment and Baseline Characteristics of the SCORHFE Trial
- trial
- randomised 1:1
Study context
- Population
- Adults aged 45 years or older with obesity and no known cardiac diseaserandomised, 746 expressed interest, 629 (84.3%) underwent eligibility assessment
- Participants
- 420 adults
- Planned comparison
- proactive multimodal heart failure screening or usual care
- Primary endpoint
- left ventricular dysfunction and/or acute heart failure hospitalisation
- Follow-up
- 1 year
No results yet. This paper sets out the design of a trial; its results are to come.
Baseline
Baseline characteristics
- Mean age
- 58.3 ± 8.4 years
- Women
- 295 participants (70.2%)
- Median body mass index
- 35.0 [32.4-38.0] kg/m²
- Central obesity, among 385 participants with available waist circumference data
- 379 (98.4%)
- Two or more cardiometabolic conditions
- Ninety-seven participants (23.1%)
Screening acceptability, among a random subset of 50 screened participants
- Considered screening duration acceptable, of the 50
- 46 (92.0%)
- Reported low procedural burden, of the 50
- 47 (94.0%)
- Supported routine implementation, of the 50
- 46 (92.0%)
Original publication
Proactive Heart Failure Screening in Obesity: Design, Recruitment and Baseline Characteristics of the SCORHFE Trial. ESC Heart Fail. Published 28 September 2026. doi:10.1093/eschf/xvag244
Summarised from the published abstract; every number is checked against it